University of Oulu

The ESHRE COVID-19 Working Group, Baris Ata, Luca Gianaroli, Kersti Lundin, Saria Mcheik, Edgar Mocanu, Satu Rautakallio-Hokkanen, Juha S Tapanainen, Nathalie Vermeulen, Anna Veiga, Outcomes of SARS-CoV-2 infected pregnancies after medically assisted reproduction, Human Reproduction, Volume 36, Issue 11, November 2021, Pages 2883–2890, https://doi.org/10.1093/humrep/deab218

Outcomes of SARS-CoV-2 infected pregnancies after medically assisted reproduction

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Author: The ESHRE COVID-19 Working Group; Ata, Baris1; Gianaroli, Luca2;
Organizations: 1Obstetrics and Gynecology Department, Koc University, Istanbul, Turkey
2Società Italiana Studi di Medicina della Riproduzione, S.I.S.Me.R. Reproductive Medicine Institute, Bologna, Emilia-Romagna, Italy
3Reproductive Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
4European Society of Human Reproduction and Embryology (ESHRE) Central Office, Grimbergen, Belgium
5Department of Reproductive Medicine, Rotunda Hospital and Royal College of Surgeons in Ireland, Dublin, Ireland
6Fertility Europe Evere, Evere, Belgium
7Department of Obstetrics and Gynaecology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
8Department of Obstetrics and Gynaecology, University of Oulu, Oulu University Hospital and Medical Research Centre, PEDEGO Research Unit, Oulu, Finland
9Reproductive Medicine Service, Dexeus Mujer, Hospital Universitari Dexeus/Institut d’Investigació Biomedica de Bellvitge, IDIBELL, Barcelona Stem Cell Bank, Regenerative Medicine Programme, Barcelona, Spain
Format: article
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 0.3 MB)
Persistent link: http://urn.fi/urn:nbn:fi-fe2022031022928
Language: English
Published: Oxford University Press, 2021
Publish Date: 2022-03-10
Description:

Abstract

STUDY QUESTION:What is the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on the outcome of a pregnancy after medically assisted reproduction (MAR)?

SUMMARY ANSWER:Our results suggest that MAR pregnancies are not differentially affected by SARS-CoV-2 infection compared to spontaneous pregnancies.

WHAT IS KNOWN ALREADY: Information on the effects of coronavirus disease 2019 (COVID-19) on pregnancy after MAR is scarce when women get infected during MAR or early pregnancy, even though such information is vital for informing women seeking pregnancy.

STUDY DESIGN, SIZE, DURATION:Data from SARS-CoV-2 affected MAR pregnancies were collected between May 2020 and June 2021 through a voluntary data collection, organised by the European Society of Human Reproduction and Embryology (ESHRE).

PARTICIPANTS/MATERIALS, SETTING, METHODS: All ESHRE members were invited to participate to an online data collection for SARS-CoV-2-infected MAR pregnancies.

MAIN RESULTS AND THE ROLE OF CHANCE:The dataset includes 80 cases from 32 countries, including 67 live births, 10 miscarriages, 2 stillbirths and 1 maternal death. An additional 25pregnancies were ongoing at the time of writing.

LIMITATIONS, REASONS FOR CAUTION: An international data registry based on voluntary contribution can be subject to selective reporting with possible risks of over- or under-estimation.

WIDER IMPLICATIONS OF THE FINDINGS: The current data can be used to guide clinical decisions in the care of women pregnant after MAR, in the context of the COVID-19 pandemic.

STUDY FUNDING/COMPETING INTEREST(S): The authors acknowledge the support of ESHRE for the data registry and meetings. J.S.T. reports grants or contracts from Sigrid Juselius Foundation, EU and Helsinki University Hospital Funds, outside the scope of the current work. The other authors declare that they have no conflict of interest.

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Series: Human reproduction
ISSN: 0268-1161
ISSN-E: 1460-2350
ISSN-L: 0268-1161
Volume: 36
Issue: 11
Pages: 2883 - 2890
DOI: 10.1093/humrep/deab218
OADOI: https://oadoi.org/10.1093/humrep/deab218
Type of Publication: A1 Journal article – refereed
Field of Science: 3123 Gynaecology and paediatrics
Subjects:
IVF
Funding: The authors acknowledge the support of ESHRE for the data registry and meetings. J.S.T. reports grants or contracts from Sigrid Juselius Foundation, EU and Helsinki University Hospital Funds, outside the scope of the current work.
Copyright information: © The Author(s) 2021. Published by Oxford University Press on behalf of European Society of Human Reproduction and Embryology. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
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