Quality of life in head and neck cancer patients at 5 years after free flap reconstruction : a significant decline during the follow-up
Lahtinen, Sanna; Molnár, Krisztina; Hietanen, Siiri; Koivunen, Petri; Ohtonen, Pasi; Alakärppä, Antti; Liisanantti, Janne (2022-01-05)
Lahtinen, S., Molnár, K., Hietanen, S. et al. Quality of life in head and neck cancer patients at 5 years after free flap reconstruction: a significant decline during the follow-up. Eur Arch Otorhinolaryngol 279, 4069–4075 (2022). https://doi.org/10.1007/s00405-021-07242-1
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https://urn.fi/URN:NBN:fi-fe2022082556301
Tiivistelmä
Abstract
Purpose: Free flap reconstructions following head and neck tumor resection are known to involve more than 50% rate of complications and other adverse events and up to 50% mortality during a 5-year follow-up.
We aimed to examine the difference in the long-term quality of life (QoL) between the 2-year and 5-year assessments after free flap surgery for cancer of the head and neck.
Methods: A total of 28 of the 39 eligible patients responded to the survey. QoL was assessed at 5 years after operation and compared with the assessment performed at 2 years after the operation using RAND-36, EORTC-C30 and H&N-35, and SWAL-QOL tools.
Results: The criteria for poor QoL using RAND-36 tool was met in 11 (39.3%) patients in contrast to 4 (14.3%, P = 0.003) patients in the 2-year assessment. EORTC-C30 global score was decreased from 83.9 (SD16.4) to 64.6 (SD 24.0, P < 0.001) during the follow-up. In both RAND-36 and EORTC-C30 surveys, decline was found in physical and role functioning together with energy and emotional well-being domains. SWAL-QOL showed poor swallowing-related QoL in both assessments.
Conclusion: We found a significant decline in QoL during a 5-year follow-up after free flap surgery for cancer of the head and neck.
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