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Quality of life in head and neck cancer patients at 5 years after free flap reconstruction : a significant decline during the follow-up |
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| Author: | Lahtinen, Sanna1,2; Molnár, Krisztina1,2; Hietanen, Siiri2; |
| Organizations: |
1Department of Anesthesiology, Oulu University Hospital (OYS), P.O. BOX 21, 90029, Oulu, Finland 2Research Group of Surgery, Anesthesiology and Intensive Care, MRC Oulu, Oulu, Finland 3Department of Otorhinolaryngology and Head and Neck Surgery, Oulu University Hospital, Oulu, Finland
4PEDEGO Research Unit, MRC Oulu, Oulu, Finland
5Department of Operative Care, Oulu University Hospital, Oulu, Finland |
| Format: | article |
| Version: | published version |
| Access: | open |
| Online Access: | PDF Full Text (PDF, 0.4 MB) |
| Persistent link: | http://urn.fi/urn:nbn:fi-fe2022082556301 |
| Language: | English |
| Published: |
Springer Nature,
2022
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| Publish Date: | 2022-08-25 |
| Description: |
AbstractPurpose: Free flap reconstructions following head and neck tumor resection are known to involve more than 50% rate of complications and other adverse events and up to 50% mortality during a 5-year follow-up. We aimed to examine the difference in the long-term quality of life (QoL) between the 2-year and 5-year assessments after free flap surgery for cancer of the head and neck. Methods: A total of 28 of the 39 eligible patients responded to the survey. QoL was assessed at 5 years after operation and compared with the assessment performed at 2 years after the operation using RAND-36, EORTC-C30 and H&N-35, and SWAL-QOL tools. Results: The criteria for poor QoL using RAND-36 tool was met in 11 (39.3%) patients in contrast to 4 (14.3%, P = 0.003) patients in the 2-year assessment. EORTC-C30 global score was decreased from 83.9 (SD16.4) to 64.6 (SD 24.0, P < 0.001) during the follow-up. In both RAND-36 and EORTC-C30 surveys, decline was found in physical and role functioning together with energy and emotional well-being domains. SWAL-QOL showed poor swallowing-related QoL in both assessments. Conclusion: We found a significant decline in QoL during a 5-year follow-up after free flap surgery for cancer of the head and neck. see all
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| Series: |
European archives of oto-rhino-laryngology |
| ISSN: | 0937-4477 |
| ISSN-E: | 1434-4726 |
| ISSN-L: | 0937-4477 |
| Volume: | 279 |
| Issue: | 8 |
| Pages: | 4069 - 4075 |
| DOI: | 10.1007/s00405-021-07242-1 |
| OADOI: | https://oadoi.org/10.1007/s00405-021-07242-1 |
| Type of Publication: |
A1 Journal article – refereed |
| Field of Science: |
3126 Surgery, anesthesiology, intensive care, radiology 3122 Cancers |
| Subjects: | |
| Funding: |
Open Access funding provided by University of Oulu including Oulu University Hospital. This study was funded by Thelma Mäkikyrö fund. |
| Copyright information: |
© The Author(s) 2022. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
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https://creativecommons.org/licenses/by/4.0/ |