University of Oulu

Tursas, L., Ylipalosaari, M., Sinikumpu, S.-P., Huilaja, L., Tasanen, K., Tiisanoja, A., Tegelberg, P., Ylöstalo, P., & Syrjälä, A.-M. (2022). Association between bleeding periodontal pockets and eczemas: Results of the Northern Finland Birth Cohort 1966. Journal of Clinical Periodontology, 49( 6), 591– 598. https://doi.org/10.1111/jcpe.13614

Association between bleeding periodontal pockets and eczemas : results of the Northern Finland Birth Cohort 1966

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Author: Tursas, Larissa1; Ylipalosaari, Merja1,2; Sinikumpu, Suvi-Päivikki3,4;
Organizations: 1Research Unit of Oral Health Sciences, Faculty of Medicine, University of Oulu, Oulu, Finland
2Medical Research Center, Oulu University Hospital and University of Oulu, Oulu, Finland
3Department of Dermatology, University Hospital of Oulu, Oulu, Finland
4Medical Research Center, PEDEGO Research Group, University of Oulu, Oulu, Finland
5Department of Oral and Maxillofacial Surgery, Oulu University Hospital, Oulu, Finland
6Dental Training Clinic, Social and Health Services, Oulu, Finland
Format: article
Version: accepted version
Access: embargoed
Persistent link: http://urn.fi/urn:nbn:fi-fe2022090857806
Language: English
Published: John Wiley & Sons, 2022
Publish Date: 2023-03-09
Description:

Abstract

Aims: To investigate whether periodontal condition measured by bleeding periodontal pockets is associated with atopic dermatitis, seborrheic dermatitis, and eczema nummulare.

Materials and methods: The study population (n=1871) was obtained from the 46-year follow-up study of the Northern Finland Birth Cohort 1966 study (NFBC1966). The periodontal condition was measured by the number of sites with bleeding periodontal pockets that were ≥ 4 mm deep. The whole skin of the participants was clinically examined, and diagnoses of skin diseases were determined according to the International Classification of Diseases (ICD-10). Prevalence rate ratios (PRR) and 95% confidence intervals (95% CI) were estimated using Poisson regression models with robust error variance.

Results: In this cohort, consisting of 46-year-old members of the Northern Finland Birth Cohort 1966, the presence of 1−3 and ≥4 bleeding deepened periodontal pockets (≥4 mm deep) were associated with seborrheic dermatitis (PRR 1.9, 95% CI: 1.3‒2.8 and PRR 2.2, 95% CI: 1.4‒3.3, respectively), and with eczema nummulare (PRR 1.7, 95% CI: 0.9‒3.1 and PRR 1.7, 95% CI: 0.9‒3.3, respectively). For non-smokers, the corresponding estimates were 1.7 for seborrheic dermatitis (95% CI: 1.1–2.6) and 1.8 (95% CI:1.1‒3.1) and 1.4 for eczema nummulare (95% CI: 0.7–2.9) and 1.2 (95% CI: 0.5–2.9), respectively. No association was found between bleeding deepened periodontal pockets and atopic dermatitis. Further adjustments for C-reactive protein, diabetes, and inflammatory diseases did not essentially change the risk estimates among either the total population or the non-smokers.

Conclusions: Bleeding periodontal pockets appeared to be associated with the presence of seborrheic dermatitis and eczema nummulare.

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Series: Journal of clinical periodontology
ISSN: 0303-6979
ISSN-E: 1600-051X
ISSN-L: 0303-6979
Volume: 49
Issue: 6
Pages: 591 - 598
DOI: 10.1111/jcpe.13614
OADOI: https://oadoi.org/10.1111/jcpe.13614
Type of Publication: A1 Journal article – refereed
Field of Science: 313 Dentistry
3121 General medicine, internal medicine and other clinical medicine
Subjects:
Funding: NFBC1966 received financial support from the University of Oulu Grant no. 24000692, Oulu University Hospital Grant no. 24301140, ERDF European Regional Development Fund Grant no. 539/2010 A31592.
Copyright information: This is the peer reviewed version of the following article: Tursas, L., Ylipalosaari, M., Sinikumpu, S.-P., Huilaja, L., Tasanen, K., Tiisanoja, A., Tegelberg, P., Ylöstalo, P., & Syrjälä, A.-M. (2022). Association between bleeding periodontal pockets and eczemas: Results of the Northern Finland Birth Cohort 1966. Journal of Clinical Periodontology, 49( 6), 591– 598 which has been published in final form at https://doi.org/10.1111/jcpe.13614. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.