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Quality of life after free flap reconstruction for the cancer of the head and neck : comparison between five-year survivors and non-survivors |
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| Author: | Molnár, Krisztina1; Hietanen, Siiri2; Liisanantti, Janne1; |
| Organizations: |
1Oulu University Hospital, Department of Anesthesiology and MRC Oulu, Research Group of Surgery, Anesthesiology and Intensive Care, Oulu, Finland 2MRC Oulu, Research Group of Surgery, Anesthesiology and Intensive Care, Oulu, Finland and Central Ostrobothnian Central Hospital, Department of Internal Medicine and Cardiology, Kokkola, Finland 3Division of Anesthesiology and Oulu University Hospital, Department of Head and Neck Surgery, MRC Oulu, PEDEGO Research Unit, Oulu, Finland |
| Format: | article |
| Version: | published version |
| Access: | open |
| Online Access: | PDF Full Text (PDF, 0.4 MB) |
| Persistent link: | http://urn.fi/urn:nbn:fi-fe2022101161583 |
| Language: | English |
| Published: |
Elsevier,
2022
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| Publish Date: | 2022-10-11 |
| Description: |
AbstractBackground: Free flap surgery due to the cancer of the head and neck includes high risk of postoperative complications and a five-year mortality up to 50%. We aimed to study the relation between the quality of life (QoL) reported two years after the operation and the mortality during a next three-year follow-up. We aimed to study the relation between the quality of life (QoL) reported two years after the operation and the mortality during a next three-year follow-up. Methods: Free flap surgery due to the cancer of the head and neck includes high risk of postoperative complications and a five-year mortality up to 50%. We aimed to study the relation between the quality of life (QoL) reported two years after the operation and the mortality during a next three-year follow-up. We aimed to study the relation between the quality of life (QoL) reported two years after the operation and the mortality during a next three-year follow-up. Results: A total of 14 (26.4%) patients died during the follow-up. The RAND-36 scores of the deceased were lower in domains “general health”, “energy”, “emotional role functioning” and “emotional well-being”. In UW-QOL tool, the domains “swallowing“ and “mood”, as well as experienced QoL were lower in the non-survivors. In EORTC QLQ assessment the non-survivors reported lower QoL in domains “global health status“, “physical functioning”, “role functioning“, “swallowing”, and “felt ill“. Conclusions: Based on our results, poor long-term survival is related to poor QoL reported two years after surgery. The difference was found in general domains of QoL tools indicating that poor QoL is a surrogate of chronic health problems having an impact on the long-term survival. see all
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| Series: |
Oral oncology |
| ISSN: | 1368-8375 |
| ISSN-E: | 1879-0593 |
| ISSN-L: | 1368-8375 |
| Volume: | 128 |
| Article number: | 105855 |
| DOI: | 10.1016/j.oraloncology.2022.105855 |
| OADOI: | https://oadoi.org/10.1016/j.oraloncology.2022.105855 |
| Type of Publication: |
A1 Journal article – refereed |
| Field of Science: |
3122 Cancers 3125 Otorhinolaryngology, ophthalmology |
| Subjects: | |
| Copyright information: |
© 2022 The Authors. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
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https://creativecommons.org/licenses/by/4.0/ |