Ollikainen, E., Saxlin, T., Tervonen, T., Suominen, A. L., Knuuttila, M., Jula, A., & Ylöstalo, P. (2022). Association between periodontal condition and blood pressure is confounded by smoking. Acta Odontologica Scandinavica, 80(6), 457–464. https://doi.org/10.1080/00016357.2022.2035430
Association between periodontal condition and blood pressure is confounded by smoking
|Author:||Ollikainen, Emilia1,2; Saxlin, Tuomas3,4; Tervonen, Tellervo1,2;|
1Research Unit of Oral Health Sciences, Faculty of Medicine, University of Oulu, Oulu, Finland
2Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland
3Institute of Dentistry, University of Eastern Finland, Kuopio, Finland
4Department of Oral and Maxillofacial Surgery, Kuopio University Hospital, Kuopio, Finland
5Public Health Evaluation and Projection Unit, Finnish Institute for Health and Welfare (THL), Kuopio, Finland
6Finnish Institute for Health and Welfare (THL), Helsinki, Finland
|Online Access:||PDF Full Text (PDF, 1.1 MB)|
|Persistent link:|| http://urn.fi/urn:nbn:fi-fe2022102863704
|Publish Date:|| 2022-10-28
Objective: To investigate the role of smoking as a confounding factor in the association between periodontal pocketing and blood pressure.
Materials and methods: After restriction to 45–64-year-old subjects without hypertension, diabetes, rheumatic diseases, obesity and with no history of cardiovascular diseases or ongoing lipid-lowering medications, the study population consisted of 307 subjects of the Health 2000 Survey in Finland. Systolic and diastolic blood pressure and pulse pressure (mmHg) were used as outcome variables. Periodontal condition was measured by the number of teeth with ≥4 mm periodontal pockets. β-estimates and 95% confidence intervals (CI) were obtained from linear regression models. Analyses were made in the whole study population and stratified according to smoking habits/history.
Results: The number of teeth with ≥4 mm periodontal pockets associated statistically significantly with systolic blood pressure and pulse pressure in the whole study population. Among never-smokers or daily smokers, there were no consistent nor statistically significant associations between the number of teeth with ≥4 mm periodontal pockets and systolic/diastolic blood pressure or pulse pressure.
Conclusions: Smoking appeared to confound the association between periodontal condition and blood pressure. Thorough control for the effect of smoking was not obtained using multivariate models.
Acta odontologica Scandinavica
|Pages:||457 - 464|
|Type of Publication:||
A1 Journal article – refereed
|Field of Science:||
The present study is part of the Health 2000 Survey (http://www.terveys2000.fi), organized by the Finnish Institute for Health and Welfare (THL) (former National Public Health Institute [KTL] of Finland). The Health 2000 Survey was partly supported by the Finnish Dental Society Apollonia. This work was supported by the Finnish Women Dentists’ Association and the Finnish Dental Society Apollonia.
The data that support the findings of this study are available from the Finnish Institute for Health and Welfare (THL) but restrictions apply to the availability of these data, which were used under licence for the current study, and are thus not publicity available. Data are, however, available from the authors upon reasonable request and with permission of the Finnish Institute for Health and Welfare.
© 2022 The Author(s). This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.