University of Oulu

Halonen, J., Hakko, H., Riala, K. et al. Familial Risk Factors in Relation to Recurrent Depression Among Former Adolescent Psychiatric Inpatients. Child Psychiatry Hum Dev 53, 515–525 (2022).

Familial risk factors in relation to recurrent depression among former adolescent psychiatric inpatients

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Author: Halonen, Joonas1; Hakko, Helinä2; Riala, Kaisa2;
Organizations: 1Research Unit of Clinical Neuroscience, Psychiatry, University of Oulu, P.O.BOX 5000, 90014, Oulu, Finland
2Department of Psychiatry, Oulu University Hospital, Oulu, P.O.BOX 26, 90029, Oulu, Finland
Format: article
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 0.6 MB)
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Language: English
Published: Springer Nature, 2022
Publish Date: 2022-12-07


Treating recurrent depression is a challenge for clinical practitioners. We investigated which family environmental factors contribute to differences between recurrent and non-recurrent depression by the young adulthood of the former adolescent inpatients. The initial sample covered 237 adolescent psychiatric inpatients with depression, of which 35.4% had later diagnosed with recurrent depression. Recurrence in depression was associated to distant maternal relationships in both male (p = 0.022) and female patients (p = 0.042). In females, the likelihood for recurrent depression was also related to psychiatric problems of the father (p = 0.013) and siblings (OR = 3.7, p = 0.032), and having a grand multiparous mother (p = 0.005). Our results emphasise the need for effective family-centred approaches in treatment of adolescents with depression.

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Series: Child psychiatry & human development
ISSN: 0009-398X
ISSN-E: 1573-3327
ISSN-L: 0009-398X
Volume: 53
Issue: 3
Pages: 515 - 525
DOI: 10.1007/s10578-021-01146-1
Type of Publication: A1 Journal article – refereed
Field of Science: 3124 Neurology and psychiatry
Funding: Open access funding provided by University of Oulu including Oulu University Hospital.
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