University of Oulu

Koskelo, M, Sinikumpu, S-P, Jokelainen, J, Huilaja, L. Risk factors of hand eczema: A population-based study among 900 subjects. Contact Dermatitis. 2022; 87( 6): 485- 491. doi:10.1111/cod.14205

Risk factors of hand eczema : a population-based study among 900 subjects

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Author: Koskelo, Marjut1; Sinikumpu, Suvi-Päivikki1; Jokelainen, Jari2;
Organizations: 1Department of Dermatology, University Hospital of Oulu, Oulu, Finland and Medical Research Center, PEDEGO Research Group, University of Oulu, Oulu, Finland
2Northern Finland Birth Cohorts, Arctic Biobank, Infrastructure for Population Studies, Faculty of Medicine, University of Oulu, Oulu, Finland
Format: article
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 0.9 MB)
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Language: English
Published: John Wiley & Sons, 2022
Publish Date: 2022-12-20


Background: Many risk factors such as atopic dermatitis (AD) have shown to associate with hand eczema (HE). However, studies concerning other atopic diseases, parental or longitudinal risk factors of HE are scarce.

Objectives: To examine the association between HE and atopic diseases, parental factors, environmental factors (keeping animals, exposure to moulds) and lifestyle factors (obesity, tobacco smoking, alcohol consumption and physical activity) at population level.

Methods: Subjects belonging to the Northern Finland Birth Cohort 1966 Study (NFBC1966) (n = 6830) answered a comprehensive health questionnaire. The data was completed with parental information.

Results: HE was reported in 900 (13.3%) individuals. All atopic diseases, parental allergy, female gender and obesity increased the risk of HE whereas physical activity decreased the risk of HE. A statistically significant association was not found between HE and tobacco smoking or alcohol consumption.

Conclusions: All atopic diseases, not only AD, seem to have influence on the presence of HE. In addition, parental and environmental factors associated with HE.

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Series: Contact dermatitis
ISSN: 0105-1873
ISSN-E: 1600-0536
ISSN-L: 0105-1873
Volume: 87
Issue: 6
Pages: 485 - 491
DOI: 10.1111/cod.14205
Type of Publication: A1 Journal article – refereed
Field of Science: 3121 General medicine, internal medicine and other clinical medicine
Copyright information: © 2022 The Authors. Contact Dermatitis published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.