University of Oulu

Uimari O, Nazri H and Tapmeier T (2021) Endometriosis and Uterine Fibroids (Leiomyomata): Comorbidity, Risks and Implications. Front. Reprod. Health 3:750018. doi: 10.3389/frph.2021.750018

Endometriosis and uterine fibroids (leiomyomata) : comorbidity, risks and implications

Saved in:
Author: Uimari, Outi1,2,3; Nazri, Hannah3; Tapmeier, Thomas3,4
Organizations: 1Department of Obstetrics and Gynecology, Oulu University, Oulu, Finland
2PEDEGO Research Unit (Research Unit for Pediatrics, Pediatric Neurology, Pediatric Surgery, Child Psychiatry, Dermatology, Clinical Genetics, Obstetrics and Gynecology, Otorhinolaryngology and Ophthalmology) and Medical Research Center Oulu, Oulu University Hospital, Oulu, Finland
3Endometriosis CaRe Centre, Nuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, United Kingdom
4Department of Obstetrics and Gynaecology, Monash University, Clayton, VIC, Australia
Format: article
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 0.5 MB)
Persistent link:
Language: English
Published: Frontiers Media, 2021
Publish Date: 2023-01-10


Uterine Fibroids (leiomyomata) and endometriosis affect millions of women world-wide. Although aetiology and natural history of the conditions are markedly different, symptoms can overlap and make differential diagnoses necessary, often using invasive methods such as laparoscopy. Considerable comorbidity exists between the two conditions and needs to be taken into account when treating fibroids and/or endometriosis. The genetic foundations of both uterine fibroids and endometriosis remain to be fully understood but recent evidence suggest common underpinnings. Here, we discuss the comorbidity of uterine fibroids and endometriosis and the implications for diagnosis, treatment and risks.

see all

Series: Frontiers in reproductive health
ISSN: 2673-3153
ISSN-E: 2673-3153
ISSN-L: 2673-3153
Volume: 3
Article number: 750018
DOI: 10.3389/frph.2021.750018
Type of Publication: A2 Review article in a scientific journal
Field of Science: 3121 General medicine, internal medicine and other clinical medicine
3123 Gynaecology and paediatrics
Copyright information: © 2021 Uimari, Nazri and Tapmeier. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.