Tikkanen, Ville MA∗; Siira, Virva PhD†; Wahlberg, Karl-Erik PhD∗; Hakko, Helinä PhD‡; Myllyaho, Toni MA∗; Läksy, Kristian MD§; Roisko, Riikka MD‡; Niemelä, Mika PhD‡,∥; Räsänen, Sami MD∗,‡. Adolescent Social Functioning Deficits in Association With Adoptive Family Functioning and Genetic Risk for Schizophrenia Spectrum Disorders: The Finnish Adoptive Family Study of Schizophrenia. The Journal of Nervous and Mental Disease 210(6):p 418-425, June 2022. | DOI: 10.1097/NMD.0000000000001483
Adolescent social functioning deficits in association with adoptive family functioning and genetic risk for schizophrenia spectrum disorders : the Finnish adoptive family study of schizophrenia
|Author:||Tikkanen, Ville1; Siira, Virva2; Wahlberg, Karl-Erik1;|
1Faculty of Medicine, Research Unit of Clinical Neuroscience, Psychiatry
2Faculty of Education, University of Oulu
3Department of Psychiatry, Oulu University Hospital, Oulu
4Social Security Institute of Finland (SSI), Helsinki
5Faculty of Medicine, Center for Life Course Health Research, University of Oulu, Oulu, Finland
|Online Access:||PDF Full Text (PDF, 0.2 MB)|
|Persistent link:|| http://urn.fi/urn:nbn:fi-fe202301255533
|Publish Date:|| 2023-06-01
Social functioning deficits (SFDs) during adolescence represent potential vulnerability indicators to schizophrenia spectrum disorders, but little is known about how both family environmental and genetic factors contribute to SFDs. The aim of this study was to examine the association of adoptees’ adolescent social functioning with adoptive family functioning and adoptees’ high (HR) or low (LR) genetic risk for schizophrenia spectrum disorders. The present subsample from the nationwide Finnish Adoptive Family Study of Schizophrenia included 88 HR and 83 LR adoptees. Adolescent social functioning was assessed using UCLA Social Attainment Survey. Assessment of adoptive family functioning was based on Global Family Ratings. Results indicated that dysfunctional family processes and high genetic risk for schizophrenia spectrum disorders contributed approximately equally to adoptees’ adolescent social functioning. Our findings underscore the importance of functional family processes in adolescent social functioning, particularly in individuals at high genetic risk for severe psychiatric disorder.
Journal of nervous and mental disease
|Pages:||418 - 425|
|Type of Publication:||
A1 Journal article – refereed
|Field of Science:||
3124 Neurology and psychiatry
V. T. has received personal research grants from the Research Foundation of the Mannerheim League for Child Welfare, Helsinki, Finland; the Alma and K.A. Snellman Foundation, Oulu, Finland; the Iso-Mällinen Foundation, Tyrnävä, Finland; and the Päivikki and Sakari Sohlberg Foundation, Helsinki, Finland. The research work of M. N. is supported by ITLA—Children's Foundation, Finland. The authors declare no conflict of interest.
© 2022 Wolters Kluwer Health, Inc. This is a non-final version of an article published in final form in Tikkanen, Ville; Siira, Virva; Wahlberg, Karl-Erik; Hakko, Helinä; Myllyaho, Toni; Läksy, Kristian; Roisko, Riikka; Niemelä, Mika; Räsänen, Sami. Adolescent Social Functioning Deficits in Association With Adoptive Family Functioning and Genetic Risk for Schizophrenia Spectrum Disorders: The Finnish Adoptive Family Study of Schizophrenia. The Journal of Nervous and Mental Disease 210(6):p 418-425, June 2022. | DOI: 10.1097/NMD.0000000000001483.