University of Oulu

Miia Marika Jansson, Martin Kögler, Sohvi Hörkkö, Tero Ala-Kokko & Lassi Rieppo (2023) Vibrational spectroscopy and its future applications in microbiology, Applied Spectroscopy Reviews, 58:2, 132-158, DOI: 10.1080/05704928.2021.1942894

Vibrational spectroscopy and its future applications in microbiology

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Author: Jansson, Miia Marika1; Kögler, Martin2; Hörkkö, Sohvi3;
Organizations: 1Research Unit of Medical Imaging, Physics and Technology, University of Oulu, Oulu, Finland
2Sensing Solutions at VTT – Technical Research Centre of Finland, Oulu, Finland
3Research Unit of Biomedicine, Medical Microbiology and Immunology, Faculty of Medicine, University of Oulu, Oulu, Finland
4Division of Intensive Care, Department of Anesthesiology, Oulu University Hospital, Oulu, Finland;e Research Group of Surgery, Anesthesiology and Intensive Care, Medical Research Center Oulu, Oulu, Finland
Format: article
Version: accepted version
Access: open
Online Access: PDF Full Text (PDF, 0.4 MB)
Persistent link: http://urn.fi/urn:nbn:fi-fe2023030630005
Language: English
Published: Informa, 2023
Publish Date: 2023-03-06
Description:

Abstract

Vibrational spectroscopic techniques, namely Fourier transform infrared (FTIR) and Raman spectroscopy, are based on the study of molecular vibrations, and they are complementary techniques to each other. This review provides an overview of the vibrational spectroscopic techniques applied in microbiology during the past decade. In addition, future applications of the elaborated spectroscopic techniques will be highlighted. The results of this review show that both FTIR and Raman spectroscopy are promising alternatives to conventional diagnostic approaches because they provide label-free and noninvasive bacterial detection, identification, and antibiotic susceptibility testing in a single step. Cost-effective, accurate, and rapid tests are needed in order to improve diagnostics and patient care, to decrease the use of unnecessary antimicrobial agents, to prevent resistant microbials, and to decrease the overall burden of outbreaks. Prior to that, however, the presented approaches need to be validated in a clinical workflow against the conventional diagnostic approaches.

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Series: Applied spectroscopy reviews
ISSN: 0570-4928
ISSN-E: 1520-569X
ISSN-L: 0570-4928
Volume: 58
Issue: 2
Pages: 132 - 158
DOI: 10.1080/05704928.2021.1942894
OADOI: https://oadoi.org/10.1080/05704928.2021.1942894
Type of Publication: A2 Review article in a scientific journal
Field of Science: 217 Medical engineering
Subjects:
Copyright information: © 2023 Applied Spectroscopy Reviews. This is an Accepted Manuscript version of the following article, accepted for publication in Applied Spectroscopy Reviews. Miia Marika Jansson, Martin Kögler, Sohvi Hörkkö, Tero Ala-Kokko & Lassi Rieppo (2023) Vibrational spectroscopy and its future applications in microbiology, Applied Spectroscopy Reviews, 58:2, 132-158, DOI: 10.1080/05704928.2021.1942894. It is deposited under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
  https://creativecommons.org/licenses/by-nc/4.0/