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Comparison of imaging parameters between OCT, GDx and HRT in the Northern Finland birth cohort eye study |
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| Author: | Stoor, Katri1; Karvonen, Elina1; Leiviskä, Ilmari1; |
| Organizations: |
1Department of Ophthalmology, PEDEGO Research Unit and Medical Research Center, University of Oulu and Oulu University Hospital, Oulu, Finland |
| Format: | article |
| Version: | accepted version |
| Access: | open |
| Online Access: | PDF Full Text (PDF, 1.2 MB) |
| Persistent link: | http://urn.fi/urn:nbn:fi-fe2023031431537 |
| Language: | English |
| Published: |
John Wiley & Sons,
2022
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| Publish Date: | 2023-03-14 |
| Description: |
AbstractPurpose: The purpose of the study was to assess and compare the optic nerve head (ONH) and retinal nerve fibre layer (RNFL) parameters and image quality parameters obtained by Cirrus HD-OCT, GDxECC and HRT3 in a population-based screening study. Methods: This analysis examined 2566 subjects taking part in the Northern Finland Birth Cohort Eye study. Images with spectral domain OCT (Cirrus HD-OCT 4000), scanning laser ophthalmoscopy (HRT3) and scanning laser polarimetry (GDxECC) were obtained from each subject. The correlation of average and regional parameters of RNFL and ONH between devices was evaluated. Results: The RNFL thickness was 90.9 µm when measured with OCT, 24.6 µm with HRT and 48.1 µm with GDx. There was a high correlation between the disc and cup measurements with the HRT and OCT and the RNFL thickness of the OCT and GDx (r > 0.5). A statistically significant correlation was found between RNFL measurements of the HRT and OCT in the superior, temporal and inferior quadrants. Optical coherence tomography (OCT) signal strength correlated with the image quality parameters of the HRT and GDx. The percentage of good quality images was the lowest with the GDx. Conclusions: The RNFL thickness in Northern Finland birth cohort was at a lower level compared to other studies. The study confirms the difference in measuring ONH parameters between the imaging devices. However, significant correlations between devices were found in the cup volume and cup disc area ratio parameters of the OCT and HRT. The correlations between image quality parameters and glaucoma detection parameters were relatively low. see all
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| Series: |
Acta ophthalmologica |
| ISSN: | 1755-375X |
| ISSN-E: | 1755-3776 |
| ISSN-L: | 1755-375X |
| Volume: | 100 |
| Issue: | 5 |
| Pages: | e1103 - e1111 |
| DOI: | 10.1111/aos.15046 |
| OADOI: | https://oadoi.org/10.1111/aos.15046 |
| Type of Publication: |
A1 Journal article – refereed |
| Field of Science: |
3125 Otorhinolaryngology, ophthalmology |
| Subjects: | |
| Funding: |
This study was supported by Glaukoma Tukisäätiö Lux, Silmäsäätiö Foundation and the Competitive StateResearch Financing of the Expert Responsibility area of Oulu University Hospital. |
| Copyright information: |
© 2021 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd. This is the peer reviewed version of the following article: Stoor, K., Karvonen, E., Leiviskä, I., Liinamaa, J. and Saarela, V. (2022), Comparison of imaging parameters between OCT, GDx and HRT in the Northern Finland birth cohort eye study. Acta Ophthalmol, 100: e1103-e1111, which has been published in final form at https://doi.org/10.1111/aos.15046. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited. |