University of Oulu

Kamil A. Moldosanov, Alexander V. Bykov, Nurlanbek Z. J. Kairyev, Mikhail K. Khodzitsky, Grigory Kropotov, Valery M. Lelevkin, Igor V. Meglinski, Andrei V. Postnikov, and Alexey A. Shakhmin "Terahertz-to-infrared converters for imaging the human skin cancer: challenges and feasibility," Journal of Medical Imaging 10(2), 023501 (14 March 2023).

Terahertz-to-infrared converters for imaging the human skin cancer : challenges and feasibility

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Author: Moldosanov, Kamil A.1; Bykov, Alexander V.2; Kairyev, Nurlanbek Z. J.1;
Organizations: 1Kyrgyz-Russian Slavic Univ. (Kyrgyzstan)
2Univ. of Oulu (Finland)
3Tydex (Russian Federation)
4Aston Univ. (United Kingdom)
5Univ. de Lorraine (France)
6Lab. de Chimie et de Physique Approche Multi-échelles des Milieux Complexes (France)
Format: article
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 2.4 MB)
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Language: English
Published: SPIE, 2023
Publish Date: 2023-03-16


Purpose: Terahertz (THz) medical imaging is a promising noninvasive technique for monitoring the skin’s conditions, early detection of the human skin cancer, and recovery from burns and wounds. It can be applied for visualization of the healing process directly through clinical dressings and restorative ointments, minimizing the frequency of dressing changes. The THz imaging technique is cost effective, as compared to the magnetic resonance method. Our aim was to develop an approach capable of providing better image resolution than the commercially available THz imaging cameras.

Approach: The terahertz-to-infrared (THz-to-IR) converters can visualize the human skin cancer by converting the latter’s specific contrast patterns recognizable in THz radiation range into IR patterns, detectable by a standard IR imaging camera. At the core of suggested THz-to-IR converters are flat matrices transparent both in the THz range to be visualized and in the operating range of the IR camera, these matrices contain embedded metal nanoparticles (NPs), which, when irradiated with THz rays, convert the energy of THz photons into heat and become nanosources of IR radiation detectable by an IR camera.

Results: The ways of creating the simplest converter, as well as a more complex converter with wider capabilities, are considered. The first converter is a gelatin matrix with gold 8.5-nm diameter NPs, and the second is a polystyrene matrix with 2-nm diameter NPs from copper–nickel MONEL® alloy 404.

Conclusions: An approach with a THz-to-IR converter equipped with an IR camera is promising in that it could provide a better image of oncological pathology than the commercially available THz imaging cameras do.

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Series: Journal of medical imaging
ISSN: 2329-4302
ISSN-E: 2329-4310
ISSN-L: 2329-4302
Volume: 10
Issue: 2
Article number: 023501
DOI: 10.1117/1.JMI.10.2.023501
Type of Publication: A1 Journal article – refereed
Field of Science: 217 Medical engineering
Funding: This work was partially supported by funding from the Academy of Finland (Grant Nos. 314639, 351068, and 325097); ATTRACT II META-HiLight project, funded by the European Union’s Horizon 2020 Research and Innovative Program (Grant No. 101004462); and the Leverhulme Trust and The Royal Society (Ref. no. APX111232, APEX Awards 2021).
Academy of Finland Grant Number: 314639
Detailed Information: 314639 (Academy of Finland Funding decision)
351068 (Academy of Finland Funding decision)
325097 (Academy of Finland Funding decision)
Copyright information: © 2023 Society of Photo‑Optical Instrumentation Engineers (SPIE). One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this publication for a fee or for commercial purposes, and modification of the contents of the publication are prohibited.