|
|
Biogenesis of mesoporous silica nanoparticles enclosed in extracellular vesicles by mouse renal adenocarcinoma cells |
|---|---|
| Author: | Pratiwi, Feby Wijaya1; Keerthanaa Balasubramanian Shanthi1; Makieieva, Olha1; |
| Organizations: |
1Laboratory of Developmental Biology, Disease Networks Research Unit, Faculty of Biochemistry and Molecular Medicine, University of Oulu and Kvantum Institute, Oulu, Finland 2Department of Chemistry, National Taiwan University, Taipei, Taiwan 3Biocenter Oulu, Department of Pathology, Oulu University Hospital, University of Oulu, Oulu, Finland
4Graduate Institute of Nanomedicine and Medical Engineering, Taipei Medical University, Taipei, Taiwan
|
| Format: | article |
| Version: | accepted version |
| Access: | embargoed |
| Persistent link: | http://urn.fi/urn:nbn:fi-fe2023050942237 |
| Language: | English |
| Published: |
Humana Press,
2023
|
| Publish Date: | 2025-05-05 |
| Description: |
AbstractIntegrating the versatility of synthetic nanoparticles to natural biomaterials, such as cells or cell membranes, has gained considerable attention as promising alternative cargo delivery platforms in recent years. Extracellular vesicles (EVs), natural nanomaterials composed of a protein-rich lipid bilayer secreted by cells, have also shown advantages and great potential as a nano delivery platform in combination with synthetic particles due to their specific natural properties in overcoming several biology hurdles possessed in the recipient cell. Therefore, the preservation of EV’s origin properties is critical for their application as nanocarriers. This chapter will describe the encapsulation procedure of MSN encapsulated in EV membrane derived from mouse renal adenocarcinoma (Renca) cells through biogenesis. The FMSN-enclosed EVs produced through this approach still contain preserved EV’s natural membrane properties. see all
|
| Series: |
Methods in molecular biology |
| ISSN: | 1064-3745 |
| ISSN-E: | 1940-6029 |
| ISSN-L: | 1064-3745 |
| ISBN: | 978-1-0716-3203-1 |
| ISBN Print: | 978-1-0716-3202-4 |
| Volume: | 2668 |
| Pages: | 241 - 256 |
| DOI: | https://doi.org/10.1007/978-1-0716-3203-1_17 |
| OADOI: | https://oadoi.org/https://doi.org/10.1007/978-1-0716-3203-1_17 |
| Host publication: |
Cell-secreted vesicles : methods and protocols |
| Host publication editor: |
Vainio, Seppo |
| Type of Publication: |
D2 Article in a professional research book (incl. editor’s introduction) |
| Field of Science: |
1182 Biochemistry, cell and molecular biology |
| Subjects: | |
| Copyright information: |
© 2023 The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature. |