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Is epileptiform activity related to developmental language disorder? : findings from the HelSLI study |
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| Author: | Lajunen, Hanna-Reetta1; Laasonen, Marja2,3; Lahti-Nuuttila, Pekka2,4; |
| Organizations: |
1Department of Clinical Neurophysiology, University of Helsinki and Helsinki University Hospital, Finland 2Department of Otorhinolaryngology and Phoniatrics, Head and Neck Surgery, Helsinki University Hospital and University of Helsinki, Helsinki, Finland 3Logopedics, School of Humanities, Philosophical Faculty, University of Eastern Finland, Joensuu, Finland
4Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki, Finland
5Unit of Analytics and Data Services, Helsinki University Hospital, Helsinki, Finland 6Research Unit of Logopedics, Faculty of Humanities, University of Oulu, Finland 7Department of Clinical Neurophysiology, University of Helsinki and Helsinki University Hospital and Epilepsia Helsinki, Finland |
| Format: | article |
| Version: | published version |
| Access: | open |
| Online Access: | PDF Full Text (PDF, 0.2 MB) |
| Persistent link: | http://urn.fi/urn:nbn:fi-fe2023051143553 |
| Language: | English |
| Published: |
Elsevier,
2023
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| Publish Date: | 2023-05-11 |
| Description: |
AbstractObjectives: To study if interictal epileptiform discharges (IEDs) are associated with language performance or pre-/perinatal factors in children with developmental language disorder (DLD). Methods: We recorded routine EEG in wake and sleep in 205 children aged 2.9–7.1 years with DLD, without neurologic diseases or intellectual disability. We examined the language performance of the children and collected data on pre-/perinatal factors. Results: Interictal epileptiform discharges were not associated with lower language performance. Children with so-called “rolandic”, i.e. centrotemporoparietal, IEDs had better language skills, but age explained this association. Most pre-/perinatal factors evaluated did not increase the risk of rolandic IEDs, except for maternal smoking (OR 4.4, 95% CI 1.4–14). We did not find electrical status epilepticus during slow-wave sleep (ESES)/spike-and-wave activation in sleep (SWAS) in any children. Conclusions: Interictal epileptiform discharges are not associated with lower language performance, and ESES/SWAS is not common in children with DLD. Significance: Routine EEGs do not bring additional information about language performance in children with DLD who do not have any neurologic diseases, seizures, intellectual disability, or regression of language development. see all
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| Series: |
Clinical neurophysiology practice |
| ISSN: | 2467-981X |
| ISSN-E: | 2467-981X |
| ISSN-L: | 2467-981X |
| Volume: | 8 |
| Pages: | 65 - 70 |
| DOI: | 10.1016/j.cnp.2023.03.004 |
| OADOI: | https://oadoi.org/10.1016/j.cnp.2023.03.004 |
| Type of Publication: |
A1 Journal article – refereed |
| Field of Science: |
6121 Languages 515 Psychology |
| Subjects: | |
| Copyright information: |
© 2023 International Federation of Clinical Neurophysiology. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
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https://creativecommons.org/licenses/by/4.0/ |