Glucose metabolism in midlife is associated with preceding 30-year employment trajectories : a Northern Finland Birth Cohort 1966 study
Varanka-Ruuska, Tuulia; Rautio, Nina; Sebert, Sylvain; Ala-Mursula, Leena (2022-10-18)
Varanka-Ruuska, Tuulia MD; Rautio, Nina PhD; Sebert, Sylvain PhD; Ala-Mursula, Leena PhD. Glucose Metabolism in Midlife Is Associated With Preceding 30-Year Employment Trajectories: A Northern Finland Birth Cohort 1966 Study. Journal of Occupational and Environmental Medicine 65(2):p 104-112, February 2023. | DOI: 10.1097/JOM.0000000000002732
© 2022 American College of Occupational and Environmental Medicine. This is a non-final version of an article published in final form in Varanka-Ruuska, Tuulia MD; Rautio, Nina PhD; Sebert, Sylvain PhD; Ala-Mursula, Leena PhD. Glucose Metabolism in Midlife Is Associated With Preceding 30-Year Employment Trajectories: A Northern Finland Birth Cohort 1966 Study. Journal of Occupational and Environmental Medicine 65(2):p 104-112, February 2023. | DOI: 10.1097/JOM.0000000000002732.
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https://urn.fi/URN:NBN:fi-fe2023053049491
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Abstract
Objective: The aim of the study is to evaluate how glucose metabolism in midlife is related to preceding 30-year-long employment trajectories.
Methods: In the Northern Finland Birth Cohort 1966, we compared glucose metabolism at 46 to employment trajectories (previously defined for men and women and named as high-educated, traditional, self-employed, delayed, and floundering; n = 6399).
Results: Compared with individuals in high-educated trajectories, odds ratios for type 2 diabetes (T2D, 95% confidence interval) in traditional and floundering trajectories in men were 1.65 (1.02–2.68) and 2.42 (1.38–4.23) and in women 1.89 (1.04–3.43) and 2.60 (1.46–4.62), respectively. In self-employed trajectory in women, odds ratios for prediabetes and T2D were 1.66 (1.09–2.51) and 2.47 (1.21–5.04).
Conclusions: The highest risks for T2D in midlife were associated after traditional and floundering trajectories in men and women and after self-employment trajectory in women.
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