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Prognostic markers for oral cancer : an overview of the current status and directions for future research |
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| Author: | de Oliveira, Lilianny Querino Rocha1; Almangush, Alhadi2,3; Al-Samadi, Ahmed3; |
| Organizations: |
1Graduate Program in Oral Biology, School of Dentistry, University of Campinas, Piracicaba, São Paulo, Brazil 2Department of Pathology, University of Turku, Turku, Finland 3Department of Oral and Maxillofacial Diseases, University of Helsinki, Helsinki, Finland
4Research Unit of Population Health, University of Oulu, Medical Research Centre, Oulu University Hospital, Oulu, Finland
5Department of Oral Diagnosis, School of Dentistry, University of Campinas, Piracicaba, São Paulo, Brazil |
| Format: | article |
| Version: | accepted version |
| Access: | embargoed |
| Persistent link: | http://urn.fi/urn:nbn:fi-fe2023053049522 |
| Language: | English |
| Published: |
John Wiley & Sons,
2023
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| Publish Date: | 2024-04-04 |
| Description: |
AbstractIn the last decades, the search for biomarkers for response to therapy and prognosis, with potential of providing information about the likely course and outcome of disease, has been intense in oral squamous cell carcinomas. Although several biomarkers, ranging from genetic and molecular alterations to clinical and histopathological features, have been described, only a few of them are used in routine practice. The aim of this review is to outline the recent advances in oral squamous cell carcinomas biomarkers, exploring those related to clinical and histopathological features, cancer cells and components of the tumor microenvironment. Future directions, highlighting the main issues that limit the clinical application of many of the potential biomarkers, are discussed. see all
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| Series: |
Journal of oral pathology & medicine |
| ISSN: | 0904-2512 |
| ISSN-E: | 1600-0714 |
| ISSN-L: | 0904-2512 |
| Volume: | 52 |
| Issue: | 4 |
| Pages: | 288 - 293 |
| DOI: | 10.1111/jop.13406 |
| OADOI: | https://oadoi.org/10.1111/jop.13406 |
| Type of Publication: |
A2 Review article in a scientific journal |
| Field of Science: |
313 Dentistry 3122 Cancers |
| Subjects: | |
| Funding: |
The Coordination of Superior Level Staff Improvement, Grant/Award Number: process#001; The National Council for Scientific and Technological Development, Grant/Award Number: process#353589/2019-1. |
| Copyright information: |
© 2023 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. This is the peer reviewed version of the following article: de Oliveira, LQR, Almangush, A, Al-Samadi, A, Salo, T, Coletta, RD. Prognostic markers for oral cancer: An overview of the current status and directions for future research. J Oral Pathol Med. 2023; 52( 4): 288- 293, which has been published in final form at https://doi.org/10.1111/jop.13406. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited. |