Heikkala, E., Paananen, M., Merikanto, I., Karppinen, J., & Oura, P. (2022). Eveningness intensifies the association between musculoskeletal pain and health-related quality of life: A Northern Finland Birth Cohort Study 1966. Pain, 163(11), 2154–2161. https://doi.org/10.1097/j.pain.0000000000002609
Eveningness intensifies the association between musculoskeletal pain and health-related quality of life : a Northern Finland Birth Cohort Study 1966
|Author:||Heikkala, Eveliina1,2,3; Paananen, Markus1,2,4; Merikanto, Ilona5,6,7;|
1Center for Life Course Health Research, University of Oulu, Oulu, Finland
2Medical Research Center Oulu, University of Oulu and Oulu University Hospital, Finland
3Rovaniemi Health Center, Rovaniemi, Finland
4Primary Health Care Services, City of Espoo, Espoo, Finland
5SleepWell Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland
6Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland
7Orton Orthopaedics Hospital, Helsinki, Finland
8Rehabilitation Services of South Karelia Social and Health Care District, Lappeenranta, Finland
9Department of Forensic Medicine, Faculty of Medicine, University of Helsinki, Helsinki, Finland
10Forensic Medicine Unit, Finnish Institute for Health and Welfare, Helsinki, Finland
|Online Access:||PDF Full Text (PDF, 0.3 MB)|
|Persistent link:|| http://urn.fi/urn:nbn:fi-fe2023060252091
|Publish Date:|| 2023-06-02
People with an evening (E)-type preference (ie, chronotype) experience musculoskeletal (MSK) pain and reduced health-related quality of life (HRQoL) more often than morning (M) types. Musculoskeletal pain is a well-established contributor to reduced HRQoL. This study aimed to evaluate whether eveningness amplifies the association between MSK pain and HRQoL in contrast to morningness. Questionnaire data on MSK pain dimensions (intensity, disability at work, number of pain sites [NPSs], and frequency), chronotype, covariates (sex, sufficiency of sleep duration, mental distress, and presence of coexisting diseases), and HRQoL (measured by 15D) were collected among 46-year-old individuals belonging to the Northern Finland Birth Cohort 1966 (N = 4257). Individuals without any MSK pain were excluded. General linear models were conducted to estimate the associations between chronotypes, MSK pain dimensions, and HRQoL. The interaction terms (chronotype × pain dimension) were tested in the models. There were 13% E-types and 43% M-types in the study sample. Each pain dimension and chronotype were related to HRQoL. In the sex-adjusted chronotype-specific models, the reduction in HRQoL in relation to pain appeared to be stronger among E-types than among M-types in respect to all pain dimensions. After adjustments, this was particularly seen in terms of NPS and pain frequency. Our findings suggest that eveningness intensifies the association between MSK pain and HRQoL, and, thus, they are indicative of E-types being more sensitive than M-types to the consequences of MSK pain. As such, MSK pain treatment and rehabilitation actions to improve HRQoL should be especially targeted at E-types.
|Pages:||2154 - 2161|
|Type of Publication:||
A1 Journal article – refereed
|Field of Science:||
3142 Public health care science, environmental and occupational health
NFBC1966 received financial support from the University of Oulu (grant no. 24000692); Oulu University Hospital (grant no. 24301140); and ERDF European Regional Development Fund (grant no. 539/2010 A31592). I. Merikanto received financial support from the Academy of Finland (project no. 322312). The funders had no role in study design, data collection and interpretation, or the decision to submit the study for publication.
© 2022 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the International Association for the Study of Pain. This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.