University of Oulu

Korhonen, T., Järvinen, J., Pesälä, J., Haapea, M., & Niinimäki, J. (2022). Modic changes associated with greater pain relief following anesthetization of the adjacent lumbar intervertebral disc: A retrospective study of chronic low back pain patients. European Journal of Radiology, 157, 110589. https://doi.org/10.1016/j.ejrad.2022.110589

Modic changes associated with greater pain relief following anesthetization of the adjacent lumbar intervertebral disc : a retrospective study of chronic low back pain patients

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Author: Korhonen, Tero1,2; Järvinen, Jyri1,2; Pesälä, Juha3;
Organizations: 1Research Unit of Medical Imaging, Physics and Technology, Faculty of Medicine, University of Oulu, PO Box 5000, 90014 Oulu, Finland
2Medical Research Center Oulu, Oulu University Hospital and University of Oulu, PO Box 8000, 90014 Oulu, Finland
3Department of Orthopaedics and Traumatology, Oulu University Hospital, PO Box 10, 90029 OYS, Oulu, Finland
4Department of Diagnostic Radiology, Oulu University Hospital, PO Box 50, 90029 OYS, Oulu, Finland
Format: article
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 0.6 MB)
Persistent link: http://urn.fi/urn:nbn:fi-fe2023061956360
Language: English
Published: Elsevier, 2022
Publish Date: 2023-06-19
Description:

Abstract

Purpose: To assess the correlation between the degree of pain relief following discoblock and the presence and type of adjacent Modic changes (MC).

Method: We retrospectively analyzed chronic low back pain (LBP) patients whose pain was suspected to originate from a specific lumbar intervertebral disc (IVD) based on a spine orthopedist’s clinical evaluation and magnetic resonance imaging (MRI). Thus, patients were selected to undergo discoblock. We calculated the degree of pain relief following discoblock on Numerical Rating Scale (ΔNRS) and analyzed the MRIs on the basis of MC presence and type on the lumbar spinal segment in question. We assessed the differences in ΔNRS between the groups with absent and present MC and the groups of MC subtypes.

Results: Forty-five patients were included in the present study, all of whom underwent discoblock at a single level. The total MC prevalence was 77.8 % (35 patients); pure or dominant MC type 1 (MC1 group) 35.6 % (16 patients); and pure or dominant MC type 2 (MC2 group) 42.2 % (19 patients). ΔNRS was significantly greater in the group with MC compared to the group without MC (median ΔNRS −5.0 vs −2.5, respectively, P = 0.043). In pairwise comparisons, a significant difference in ΔNRS was found between the MC1 group and the group without MC (median ΔNRS −5.0 vs −2.5, respectively, P = 0.012).

Conclusions: We propose that MC type 1 are associated with lumbar spinal pain, and that the pain arises at least partly from the adjacent IVD or endplate.

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Series: European journal of radiology
ISSN: 0720-048X
ISSN-E: 1872-7727
ISSN-L: 0720-048X
Volume: 157
Article number: 110589
DOI: 10.1016/j.ejrad.2022.110589
OADOI: https://oadoi.org/10.1016/j.ejrad.2022.110589
Type of Publication: A1 Journal article – refereed
Field of Science: 3126 Surgery, anesthesiology, intensive care, radiology
Subjects:
Copyright information: © 2022 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
  https://creativecommons.org/licenses/by/4.0/