University of Oulu

Mirkka J. Hirvonen, Rafael Pasternack, Tiina Lipitsä, Armi Vihervaara, Rauno Harvima, Martta Ranta, Harri Sintonen, Laura Huilaja; Patients with Hidradenitis Suppurativa Suffer from Low Health-Related Quality of Life as Measured by the Generic 15D Instrument. Skin Appendage Disord 2 May 2022; 8 (3): 221–227.

Patients with hidradenitis suppurativa suffer from low health-related quality of life as measured by the generic 15D instrument

Saved in:
Author: Hirvonen, Mirkka J.1; Pasternack, Rafael2; Lipitsä, Tiina3;
Organizations: 1AbbVie Oy, Espoo, Finland
2Department of Dermatology, Tampere University Hospital and Tampere University, Tampere, Finland
3Department of Dermatology, Kuopio University Hospital and University of Eastern Finland, Kuopio, Finland
4Department of Dermatology, Turku University Hospital, Turku, Finland
5Department of Public Health, University of Helsinki, Helsinki, Finland
6Department of Dermatology and Medical Research Center Oulu, Oulu University Hospital, PEDEGO Research Unit, University of Oulu, Oulu, Finland
Format: article
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 0.3 MB)
Persistent link:
Language: English
Published: Karger, 2021
Publish Date: 2023-06-21


Introduction: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease associated with various comorbidities and diminished quality of life (QoL). Among dermatological conditions, HS is reported to most severely diminish QoL. This study aimed to analyse the health-related QoL (HRQoL) of patients with HS in more detail by using generic to disease-specific HRQoL questionnaires. Correlations between the HRQoL measures and HS disease severity measures were assessed.

Methods: We analysed the HRQoL and clinical severity of patients with HS (N = 92) treated in 5 Finnish hospitals using HRQoL measurement tools most often used in dermatological clinics, as well as the generic 15D instrument (standardized and self-administered 15-dimensional measure of HRQoL). The disease severity was assessed using the Hurley stage, International Hidradenitis Suppurativa Severity Score System, and disease severity evaluation by the investigator.

Results: The mean 15D score of HS patients was low and comparable with that of patients with cancers. No correlation was found between HS severity measures and 15D score, indicating that even mild HS has a high impact on HRQoL.

Conclusions: Our findings strengthen the understanding about HS as a debilitating disease and even compared with non-dermatological conditions and highlight the need of comprehensive care of patients with HS.

see all

Series: Skin appendage disorders
ISSN: 2296-9195
ISSN-E: 2296-9160
ISSN-L: 2296-9195
Volume: 8
Issue: 3
Pages: 221 - 227
DOI: 10.1159/000520839
Type of Publication: A1 Journal article – refereed
Field of Science: 3121 General medicine, internal medicine and other clinical medicine
Funding: The design, study conduct, and financial support for the study were provided by AbbVie. AbbVie participated in the interpretation of data, review, and approval of the publication.
Copyright information: © 2021 The Author(s). Published by S. Karger AG, Basel. This article is licensed under the Creative Commons Attribution 4.0 International License (CC BY) ( Usage, derivative works and distribution are permitted provided that proper credit is given to the author and the original publisher.