University of Oulu

Vesikansa, A., Mehtälä, J., Pesu, M., Aaltonen, J., Konttinen, R., Tasanen, K., & Huilaja, L. (2023). Comorbidities and Medication Use in Finnish Patients with Psoriasis: A Population-Based Registry Study. Acta Dermato-Venereologica, 103, adv00886.

Comorbidities and medication use in Finnish patients with psoriasis : a population-based registry study

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Author: Vesikansa, Aino1; Mehtälä, Juha1; Pesu, Marko2,3;
Organizations: 1MedEngine Oy, Helsinki, Finland
2AbbVie Oy, Helsinki
3ilead Sciences Finland Oy, Vantaa
4Department of Dermatology and Medical Research Center, Oulu University Hospital; Research Group of Clinical Medicine, University of Oulu, Oulu, Finland
Format: article
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 0.8 MB)
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Language: English
Published: Society for Publication of Acta Dermato-Venereologica, 2023
Publish Date: 2023-08-17


Therapeutic options for psoriasis vulgaris have changed during recent decades with the introduction of biologics. Few nationwide studies are available on psoriasis treatment patterns, and those from Finland predate the use of biologics. The aim of this retrospective, population-based registry study was to identify patients with psoriasis vulgaris and their treatment patterns in the secondary care setting in Finland. The study cohort included 41,456 adults with a diagnosis of psoriasis vulgaris in the public secondary healthcare setting from 2012 through 2018. Data on comorbidities, pharmacotherapy, and phototherapy were collected from nationwide healthcare and drug registries. Patients in the cohort had a wide range of comorbidities, with 14.9% having psoriatic arthritis. Treatment was based largely on topical and conventional systemic medications. Conventional medications were used by 28.9% of patients, and methotrexate was the most common option (20.9%). Biologics were used by 7.3% of patients, mostly as second- and third-line treatment. The use of conventional systemic medications, topical treatments, and phototherapy decreased after the initiation of biologics. This study of psoriasis vulgaris in Finland provides a framework for the development of future care practices.

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Series: Acta dermato-venereologica
ISSN: 0001-5555
ISSN-E: 1651-2057
ISSN-L: 0001-5555
Volume: 103
Article number: adv00886
DOI: 10.2340/actadv.v103.3491
Type of Publication: A1 Journal article – refereed
Field of Science: 3121 General medicine, internal medicine and other clinical medicine
Funding: The design, study conduct, and financial support for the study were provided by AbbVie. AbbVie participated in the interpretation of data, review, and approval of the publication. No honoraria or payments were made for authorship.
Copyright information: © 2023 Aino Vesikansa, Juha Mehtälä, Marko Pesu, Jaakko Aaltonen, Riikka Konttinen, Kaisa Tasanen, Laura Huilaja. Published by Medical Journals Sweden, on behalf of the Society for Publication of Acta Dermato-Venereologica. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (