Anttonen, V, Pöykkö, E, Kiviniemi, E, Jokelainen, J, Huilaja, L, Sinikumpu, S-P. Characteristics, comorbidities, and treatment practices of lichen planus in Northern Finland: a register-based study among 619 subjects. Health Sci Rep. 2023; 6:e1327. doi: https://doi.org/10.1002/hsr2.1327
Characteristics, comorbidities, and treatment practices of lichen planus in Northern Finland : a register-based study among 619 subjects
|Author:||Anttonen, Veera1; Pöykkö, Elia1; Kiviniemi, Eetu2;|
1Faculty of Medicine, University of Oulu, Oulu, Finland
2Faculty of Medicine, Northern Finland Birth Cohorts, Arctic Biobank, and Infrastructure for Population Studies, Oulu, Finland
3Faculty of Medicine, Research Unit of Clinical Medicine, Northern Finland Birth Cohorts, Arctic Biobank, and Infrastructure for Population Studies, University of Oulu, Oulu, Finland
4Department of Dermatology, Finland and Research Unit of Clinical Medicine, Oulu University Hospital, University of Oulu, Oulu, Finland
|Online Access:||PDF Full Text (PDF, 0.9 MB)|
|Persistent link:|| http://urn.fi/urn:nbn:fi-fe2023081897855
John Wiley & Sons,
|Publish Date:|| 2023-08-18
Background and Aims: Lichen planus (LP) is a common itching skin disease where lesions appear on the skin and mucous membranes. However, the epidemiology of LP is not yet sufficiently understood. The aim of this study was to retrospectively map out the characteristics, comorbidities and treatments of patients diagnosed with LP.
Methods: This is a retrospective hospital patient registry-based study performed between 2009 and 2021 in a secondary care hospital (Oulu University Hospital) in Northern Finland. All patients with recorded diagnosis of LP were included in the study. Characteristics, comorbidities, and treatments of LP patients were studied.
Results: In total, 619 patients were verified from the hospital health records. The mean age of patients was 54.2 years and the majority were female (58.3%). Most of the patients had symptoms in more than two skin areas (mean 2.7 skin areas), lower limbs being the most common site (74.0%). A third of patients (34.7%) had oral LP lesions. Nearly fifth (19.4%) of the subjects had a history of previous LP. Of comorbidities found among LP subjects, obesity (22.5%), malignancies (19.4%), depression (12.8%), and thyroiditis (12.4%) were seen more often than in general Finnish population. The most used form of treatment was topical corticosteroids (97.6%), followed by phototherapy 26.8%. Systemic treatments such as prednisolone and methotrexate had been used in 7.6% and 1.1% of the patients, respectively.
Conclusion: LP patients had a heightened risk for several comorbidities, which should be considered when managing patients with LP.
Health science reports
|Type of Publication:||
A1 Journal article – refereed
|Field of Science:||
3121 General medicine, internal medicine and other clinical medicine
© 2023 The Authors. Health Science Reports published by Wiley Periodicals LLC. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.