University of Oulu

Suvela, R, Niemelä, M, Perämäki, P. Determination of xanthates as Cu(II) complexes by high-performance liquid chromatography – Inductively coupled plasma tandem mass spectrometry. J Sep Sci. 2023; 46:2300176.

Determination of xanthates as Cu(II) complexes by high-performance liquid chromatography : inductively coupled plasma tandem mass spectrometry

Saved in:
Author: Suvela, Ronja1; Niemelä, Matti1; Perämäki, Paavo1
Organizations: 1Research Unit of Sustainable Chemistry, University of Oulu, Oulu, Finland
Format: article
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 1.2 MB)
Persistent link:
Language: English
Published: John Wiley & Sons, 2023
Publish Date: 2023-08-29


The present study provides a novel, selective analysis method for the determination of low xanthate concentrations. The rising concern over the environmental effects of xanthates demands the development of analysis methods which this study answers. Complex formation in aqueous solution between xanthates and an excess of Co(II), Ni(II), Pb(II), Cd(II), Cu(II), and Zn(II) ions was utilized to selectively determine xanthates by high-performance liquid chromatography–inductively coupled plasma tandem mass spectrometry for the first time. The complexes that were formed were extracted to ethyl acetate using liquid–liquid extraction and separated by high-performance liquid chromatography technique before the quantitative determination of metal ions and sulfur in the xanthate complexes. Good separation and high measurement sensitivity were achieved using Cu(II) as the complex metal ion. The analysis method was optimized for the determination of sodium isopropyl xanthate and sodium isobutyl xanthate with detection limits of 24.7 and 13.3 μg/L, respectively. With a linear calibration range of 0.1–15 mg/L and a total analysis time of 4–5 min, the present method is a fast and sensitive option for selective xanthate determination.

see all

Series: Journal of separation science
ISSN: 1615-9306
ISSN-E: 1615-9314
ISSN-L: 1615-9306
Volume: 46
Issue: 16
Article number: 2300176
DOI: 10.1002/jssc.202300176
Type of Publication: A1 Journal article – refereed
Field of Science: 116 Chemical sciences
Funding: The contribution of R. Suvela to this study was supported by the Technology and Natural Sciences Doctoral Program of the University of Oulu.
Copyright information: © 2023 The Authors. Journal of Separation Science published by Wiley-VCH GmbH. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivsLicense, which permits use and distribution in any medium,provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.