University of Oulu

Anna-Leena Heikkinen, Teemu I. Paajanen, Christer Hublin, Teppo Valtonen, Johanna Krüger, Veera Tikkanen, Toni Saari, Anne M. Koivisto, Tuomo Hänninen & Anne M. Remes (2023) The Cognitive Function at Work Questionnaire in memory clinic setting: a validation study, Journal of Clinical and Experimental Neuropsychology, 45:4, 365-376, DOI: 10.1080/13803395.2023.2239508

The Cognitive Function at Work Questionnaire in memory clinic setting : a validation study

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Author: Heikkinen, Anna-Leena1,2,3,4; Paajanen, Teemu I.4; Hublin, Christer4;
Organizations: 1Research Unit of Clinical Medicine, Neurology, University of Oulu, Oulu, Finland
2MRC, Oulu University Hospital, Oulu, Finland
3Neurocenter, Neurology, Oulu University Hospital, Oulu, Finland
4Work Ability and Working Careers, Finnish Institute of Occupational Health, Helsinki, Finland
5Neurocenter, Neurology, Kuopio University Hospital, Kuopio, Finland
6Unit of Neurology, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland
7Department of Geriatrics, Helsinki University Hospital, Helsinki, Finland
8Clinical Neurosciences, University of Helsinki, Helsinki, Finland
Format: article
Version: accepted version
Access: embargoed
Persistent link: http://urn.fi/urn:nbn:fi-fe20230913124862
Language: English
Published: Informa, 2023
Publish Date: 2024-08-10
Description:

Abstract

Introduction: As there is a trend toward more people seeking medical help due to cognitive symptoms, validated and targeted questionnaires are increasingly important in the clinical evaluation process. The Cognitive Function at Work Questionnaire (CFWQ) was developed to identify and rate subjective cognitive symptoms of individuals active in working life. However, its psychometric characteristics have not been previously studied in a memory clinic setting.

Method: The factorial structure, internal consistency, test-retest reliability, and convergent validity of the CFWQ were studied in a memory clinic setting (N = 113). We also investigated the instrument’s ability to identify cognitive symptoms in a cohort of early-onset dementia (EOD, N = 22), mild cognitive impairment-neurological (MCI-n, N = 18), MCI due to mood, sleep, or other physical health problems (MCI-o, N = 59), and subjective cognitive decline (SCD, N = 14) patients.

Results: Based on factor analysis, eight cognitive subscales were identified covering main cognitive domains: Memory, Language, Executive Function, Speed of Processing, Cognitive Control, Name Memory, Visuospatial/Praxis and Attention. The internal consistency (α = 0.93) and the test-retest reliability (ICC = 0.91) were high. Several correlations (r = 0.19 — 0.33, p < 0.05) were documented between neuropsychological impairment level and CFWQ scores. EOD, MCI-n, MCI-o, and SCD groups did not differ statistically significantly in the levels of cognitive symptoms as measured by the CFWQ Total score. EOD group scored higher (p = 0.009) than other patient groups on the Visuospatial/Praxis subscale, but the difference between EOD and MCI-o groups turned insignificant after correcting for multiple testing.

Conclusions: The results of the study support the validity and reliability characteristics of the CFWQ in a memory clinic setting. The instrument is easy-to-use and has clinical utility in capturing the subjective cognitive symptoms of patients active in working life and who need a referral to a more detailed evaluation.

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Series: Journal of clinical and experimental neuropsychology
ISSN: 1380-3395
ISSN-E: 1744-411X
ISSN-L: 1380-3395
Volume: 45
Issue: 4
Pages: 365 - 376
DOI: 10.1080/13803395.2023.2239508
OADOI: https://oadoi.org/10.1080/13803395.2023.2239508
Type of Publication: A1 Journal article – refereed
Field of Science: 3124 Neurology and psychiatry
Subjects:
Funding: This work was supported by the Academy of Finland [315460]; the University of Oulu Scholarship Foundation;the Finnish Brain Foundation [20190012]; and the Finnish Work Environment Fund [180038].
Academy of Finland Grant Number: 315460
Detailed Information: 315460 (Academy of Finland Funding decision)
Copyright information: © 2023 Informa UK Limited, trading as Taylor & Francis Group. This is an Accepted Manuscript version of the following article, accepted for publication in Journal of Clinical and Experimental Neuropsychology. Anna-Leena Heikkinen, Teemu I. Paajanen, Christer Hublin, Teppo Valtonen, Johanna Krüger, Veera Tikkanen, Toni Saari, Anne M. Koivisto, Tuomo Hänninen & Anne M. Remes (2023) The Cognitive Function at Work Questionnaire in memory clinic setting: a validation study, Journal of Clinical and Experimental Neuropsychology, 45:4, 365-376, DOI: 10.1080/13803395.2023.2239508. It is deposited under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.
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