Amendments of weld formation in human skin laser soldering
|Author:||Ryabkin, Dmitrii1,2; Meglinsk, Igor3,4; Gerasimenko, Alexander1,2|
1Institute of Biomedical Systems, National Research University of Electronic Technology, Moscow, Russia
2Institute for Bionic Technologies and Engineering, I.M. Sechenov First Moscow State Medical University, Moscow, Russia
3Optoelectronics and Measurement Techniques, University of Oulu, Oulu, Finland
4College of Engineering and Physical Sciences, Aston University, Birmingham, UK
|Persistent link:|| http://urn.fi/urn:nbn:fi-fe20230914125321
John Wiley & Sons,
|Publish Date:|| 2024-08-03
A computational modeling is employed for quantitative assessment of weld formation and area of tissue temperature necrosis during the human skin laser soldering. The evaluation is carried out depending on the components composition of using solders, including bovine serum albumin (BSA), indocyanine green (ICG), and carbon nanotubes (CNTs), as well as the angle of incidence of laser light and its pulse duration. The influence of CNT on the change of thermodynamic characteristics of albumin denaturation and the rate of formation of the laser weld is investigated. The obtained results suggest to limit the duration of laser light pulse by temperature relaxation time to minimize transfer of thermal energy to reduce the heating of human skin tissues. The developed model has a great potential for further optimization of laser soldering of biological tissues technology with greater efficiency in minimizing the weld area.
Journal of biophotonics
|Type of Publication:||
A1 Journal article – refereed
|Field of Science:||
217 Medical engineering
Development of weld formation model in human skin laser soldering and research by differential scanning calorimetry method was supported by the Russian Science Foundation grant No. 22-75-00089, https://rscf.ru/project/22-75-00089/. This research work was supported by the Academic leadership program Priority 2030 proposed by Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University) and partially supported by the Academy of Finland (grant 325097).
|Academy of Finland Grant Number:||
325097 (Academy of Finland Funding decision)
© 2023 Wiley-VCH GmbH. This is the peer reviewed version of the following article: Ryabkin, D., Meglinsk, I., Gerasimenko, A., J. Biophotonics 2023, 16(8), e202300070, which has been published in final form at https://doi.org/10.1002/jbio.202300070. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.