University of Oulu

Saarinen, H. J., Pohjantähti-Maaroos, H., Antikainen, R., Lahtela, J. T., & Palomäki, A. (2023). The Effect of Physical Activity on Arterial Stiffness, Inflammation and Lipoproteins among 30–65-Year-Old Men. Physical Activity and Health, 7(1), pp. 143–152. DOI:

The effect of physical activity on arterial stiffness, inflammation and lipoproteins among 30–65-year-old men

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Author: Saarinen, Harri J.1; Pohjantähti-Maaroos, Hanna1; Antikainen, Riitta2;
Organizations: 1Tampere Heart Hospital, Finland
2Center for Life Course Health Research, University of Oulu, Finland
3Tampere University Hospital, Finland
4Kanta-Häme Central Hospital, Finland
Format: article
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 0.9 MB)
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Language: English
Published: Ubiquity Press, 2023
Publish Date: 2023-09-25


Introduction: Obesity and an inactive lifestyle increase risk for metabolic syndrome and cardiovascular disease. We did a cross-sectional study on 120 men with and 80 men without metabolic syndrome to investigate the connection between patient-reported physical activity and cardiovascular risk factors.

Methods: The subjects’ daily amount of physical exercise was assessed with a structured questionnaire regarding normal weekly amount, type and mode of physical activity. The subjects were stratified into different groups regarding their physical activity and metabolic syndrome status. We compared lipid levels, resting heart rate, hs-CRP, HbA1c and arterial elasticity of the subjects in different groups.

Results: Subjects with metabolic syndrome and high amounts of daily physical activity had higher resting heart rate, hs-CRP, triglycerides and lower HDL cholesterol than their counterparts without metabolic syndrome who reported lower levels of daily physical activity.

Conclusions: An increase in daily physical activity was associated with lower HbA1c among men with metabolic syndrome up to the level of subjects without metabolic syndrome. Increasing physical activity solely is an insufficient strategy for improving all the unfavorable cardiovascular risk factors related to metabolic syndrome.

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Series: Physical activity and health
ISSN: 2515-2270
ISSN-E: 2515-2270
ISSN-L: 2515-2270
Volume: 7
Issue: 1
Pages: 143 - 152
DOI: 10.5334/PAAH.230
Type of Publication: A1 Journal article – refereed
Field of Science: 3121 General medicine, internal medicine and other clinical medicine
Funding: This work was supported by research grant from the Orion Research Foundation sr. None of the sponsors had a role in any aspect of the present study, including design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, approval of the manuscript, and decision to submit the manuscript for publication.
Copyright information: © 2023 The Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC-BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See