University of Oulu

H. Ferdinando, A. Zienkiewicz, A. Abdelsamie, E. Vihriälä, M. Huotari, and T. Myllylä "An experimental study of the photoplethysmography waveform analysis on different vessel wall thickness", Proc. SPIE 12378, Dynamics and Fluctuations in Biomedical Photonics XX, 123780A (7 March 2023);

An experimental study of the photoplethysmography waveform analysis on different vessel wall thickness

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Author: Ferdinando, Hany1,2; Zienkiewicz, Aleksandra3; Abdelsamie, Abdelrahman3;
Organizations: 1Research Unit of Health Science and Technology, Faculty of Medicine, University of Oulu, Finland
2Department of Electrical Engineering, Petra Christian University, Indonesia
3Optoeletronics and Measurement Technique Research Unit, University of Oulu, Finland
4Biomimetics and Intelligent Systems Group, University of Oulu, Oulu, Finland
Format: article
Version: accepted version
Access: open
Online Access: PDF Full Text (PDF, 0.3 MB)
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Language: English
Published: SPIE, 2023
Publish Date: 2023-10-09


Photoplethysmography (PPG) waveform is primary formed by absorbance and scattering of light caused by blood volume changes in the microvascular bed of tissue. The volume of blood is constantly changing due to cardiac activity and various low frequency physiological components, such as, respiration and sympathetic nervous system. Importantly, elastic property of blood vessels and blood pressure also greatly affects the volume of blood and thus PPG waveform inversely contains information on vessel elasticity and pressure that has been studied using e.g., pulse decomposition analysis (PDA) models. We emulated PPG waveform by using a simplified mock circulatory loop mimicking human circulatory system to study how changing elasticity of 3D printed vessels and blood pressure affects the PPG waveform, aiming to validate presented pulse decomposition analysis model for estimating vessel stiffness and blood pressure. The circulatory system built for the study is controlled via custom-made LabView software. Pumping frequency, pressure and flow of blood mimicking liquid can be controlled and accurately measured for a reference. The main analysis relied on the PDA that extracted five log-normal pulses for further analysis. In particular, we focused on the centre parameter of each log-normal pulse and observed it changes depending on the emulated parameters.

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Series: Progress in biomedical optics and imaging
ISSN: 1605-7422
ISSN-E: 2410-9045
ISSN-L: 1605-7422
ISBN: 978-1-5106-5862-2
ISBN Print: 978-1-5106-5861-5
Volume: 24
Issue: 27
Article number: 123780A
DOI: 10.1117/12.2650629
Host publication: Dynamics and Fluctuations in Biomedical Photonics XX 2023
Host publication editor: Tuchin, Valery V.
Leahy, Martin J.
Wang, Ruikang K.
Zalevsky, Zeev
Conference: Dynamics and Fluctuations in Biomedical Photonics
Type of Publication: A4 Article in conference proceedings
Field of Science: 217 Medical engineering
Copyright information: © (2023) Society of Photo‑Optical Instrumentation Engineers (SPIE). One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this publication for a fee or for commercial purposes, and modification of the contents of the publication are prohibited.