University of Oulu

Simulation study on acousto-optics sensing of focused ultrasound

Saved in:
Author: Sonker, Deepak1
Organizations: 1University of Oulu, Faculty of Medicine, Health Sciences
Format: ebook
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 2.4 MB)
Pages: 63
Persistent link:
Language: English
Published: Oulu : D. Sonker, 2022
Publish Date: 2022-06-15
Thesis type: Master's thesis
Tutor: Myllylä, Teemu
Bykau, Aliaksander
Reviewer: Jämsä, Timo
Myllylä, Teemu


The acousto-optics (AO) technique can provide a good contrast with high penetration depth (up to 5 cm) and can be potentially utilized in real time monitoring of the focused ultrasound (FUS) therapies. This work presents the AO simulation study on the interaction of light and FUS in the single-layer brain (SLB) medium and four-layer brain (FLB) medium. FUS pressure distribution at 0.5 MHz and 0.9 MHz frequency was simulated on k-Wave toolbox and the AO Monte Carlo (MC) algorithm was developed on MATLAB to simulate the AO effect in both mediums. The result for the SLB for both ultrasound (US) frequencies suggests that the modulation depth (MD) is high in the region of US focus with a magnitude of 2%-3% and <1% at 0.5 MHz and 0.9 MHz, respectively. Moreover, the MD decreases to 5 orders of magnitude at the source region. In the FLB, the MD decreased to 4–4.5 orders at the source and was present in the skull and US focus region with a magnitude of <1% at both US frequencies. These results suggest that AO can be utilized in sensing FUS effects on brain tissue and the AO signal-to-noise ratio (SNR) depends not only on the MD but also on the level of light intensity interacting with the US pressure.

see all

Copyright information: © Deepak Sonker, 2022. This publication is copyrighted. You may download, display and print it for your own personal use. Commercial use is prohibited.