University of Oulu

iNEXT - Infrastructure for NMR, EM and X-rays for translational research (653706)

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Description:
Structural biology provides insight into the molecular architecture of cells up to atomic resolution, revealing the biological mechanisms that are fundamental to life. It is thus key to many innovations in chemistry, biotechnology and medicine such as engineered enzymes, new potent drugs, innovative vaccines and novel biomaterials. iNEXT (infrastructure for NMR, EM and X-rays for Translational research) will provide high-end structural biology instrumentation and expertise, facilitating expert and non-expert European users to translate their fundamental research into biomedical and biotechnological applications. iNEXT brings together leading European structural biology facilities under one interdisciplinary organizational umbrella and includes synchrotron sites for X-rays, NMR centers with ultra-high field instruments, and, for the first time, advanced electron microscopy and light imaging facilities. Together with key partners in biological and biomedical institutions, partners focusing on training and dissemination activities, and ESFRI projects (Instruct, Euro-BioImaging, EU-OPENSCREEN and future neutron-provider ESS), iNEXT forms an inclusive European network of world class. iNEXT joint research projects (fragment screening for drug development, membrane protein structure, and multimodal cellular imaging) and networking, training and transnational access activities will be important for SMEs, established industries and academics alike. In particular, iNEXT will provide novel access modes to attract new and non-expert users, which are often hindered from engaging in structural biology projects through lack of instrumentation and expertise: a Structural Audit procedure, whereby a sample is assessed for its suitability for structural studies; Enhanced Project Support, allowing users to get expert help in an iNEXT facility; and High-End Data Collection, enabling experienced users to take full benefit of the iNEXT state-of-the-art equipment.
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Subjects:
Grant Number: 653706
Cordis Record Number: 194892
Project Start Date: 2015-09-01
Project End Date: 2019-08-31
Project Funder: EC/H2020/RIA/
EC Special Clause: false
Datapilot: false
Open Access Mandate: true
Coordinator: UNIVERSITEIT UTRECHT
Coordinator EU Contribution: 999724
EU Max Contribution: 9999534.25
Total Cost: 9999534.25
Participant: EOTVOS LORAND TUDOMANYEGYETEM
Société Civile Synchrotron SOLEIL
EUROPEAN MOLECULAR BIOLOGY LABORATORY
EUROPEAN SPALLATION SOURCE ESS AB
Masarykova univerzita
STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS
AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS
WEIZMANN INSTITUTE OF SCIENCE
DIAMOND LIGHT SOURCE LIMITED
CONSORZIO INTERUNIVERSITARIO RISONANZE MAGNETICHE DI METALLO PROTEINE
ACADEMISCH ZIEKENHUIS LEIDEN
EUROPEAN SYNCHROTRON RADIATION FACILITY
AARHUS UNIVERSITET
FORSCHUNGSVERBUND BERLIN EV
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
UNIVERSITEIT LEIDEN
JOHANN WOLFGANG GOETHE UNIVERSITAET FRANKFURT AM MAIN
OULUN YLIOPISTO
INSTITUTO DE TECNOLOGIA QUIMICA E BIOLOGICA - UNIVERSIDADE NOVA DE LISBOA
LUNDS UNIVERSITET
PANEPISTIMIO PATRON
INSTRUCT ACADEMIC SERVICES LIMITED
More information: Detailed project information (CORDIS)
Detailed project information (Openaire)
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