University of Oulu

CoroPrevention - Personalized Prevention for Coronary Heart Disease (848056)

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Description:
European Coronary Heart Disease (CHD) burden is unsustainable. Better risk stratification tools and personalized care of patients are needed for reducing morbidity and mortality of CHD and the associated economic burden. To this end we have planned to shape and implement a personalized secondary prevention program for patients with established CHD. This precision strategy will be tested in a prospective trial, the CoroPrevention Trial, a central element of our proposal. We aim to significantly reduce the numbers of coronary events by using outcome risk- and patient characteristics- guided prevention in CHD patients. 1. Prospectively evaluate clinical utility of personalized prevention in CHD 2. Evaluate health economic and social benefits of the personalized prevention in CHD 3. Discover predictive markers of drug treatment response in CHD 4. Improve current ESC guidelines based on RCT validated clinical data 5. Disseminate the refined prevention program to the attention of practitioners, patients, health care payers and policy makers This program will establish a new economically sustainable personalized treatment practice applicable throughout Europe particularly to those regions where CHD prevention needs upgrading. The used protocols and technologies will carefully assessed by NICE using their standard evaluation methods that will allow independent expert opinions for different European authorities and decision makers. These opinion statements will further be supported by full Health Economics analyses of CoroPrevention Trial.
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Subjects:
Grant Number: 848056
Cordis Record Number: 226668
Project Start Date: 2020-01-01
Project End Date: 2026-12-31
Project Funder: EC/H2020/IA/
EC Special Clause: false
Datapilot: true
Open Access Mandate: true
Coordinator: TAMPEREEN KORKEAKOULUSAATIO SR
Coordinator EU Contribution: 3387774
EU Max Contribution: 19970827.26
Total Cost: 22168724.75
Participant: UNIVERSITEIT HASSELT
SYNLAB HOLDING DEUTSCHLAND GMBH
HELSINGIN JA UUDENMAAN SAIRAANHOITOPIIRIN KUNTAYHTYMÄ
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
UNIWEB
OULUN YLIOPISTO
THE UNIVERSITY OF SHEFFIELD
LAKKA TECHNOLOGIES OY
SOCIETE EUROPEENNE DE CARDIOLOGIE
RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG
CROWN CRO OY
IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON
ZORA BIOSCIENCES OY
NATIONAL INSTITUTE FOR HEALTH AND CARE EXCELLENCE
FACULDADE DE MEDICINA DA UNIVERSIDADE DE LISBOA
CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III (F.S.P.)
CHARITE - UNIVERSITAETSMEDIZIN BERLIN
IRCCS OSPEDALE POLICLINICO SAN MARTINO
UNIWERSYTET JAGIELLONSKI
More information: Detailed project information (CORDIS)
Detailed project information (Openaire)
Copyright information: © European Union, 1994-2017 CORDIS, http://cordis.europa.eu/
All materials created by the OpenAIRE consortium are licensed under a Creative Commons Attribution 4.0 International License
  http://cordis.europa.eu/
https://creativecommons.org/licenses/by/4.0/