Quality of life after free flap reconstruction for the cancer of the head and neck : comparison between five-year survivors and non-survivors
Molnár, Krisztina; Hietanen, Siiri; Liisanantti, Janne; Koivunen, Petri; Lahtinen, Sanna (2022-04-08)
Molnár, K., Hietanen, S., Liisanantti, J., Koivunen, P., & Lahtinen, S. (2022). Quality of life after free flap reconstruction for the cancer of the head and neck: Comparison between five-year survivors and non-survivors. Oral Oncology, 128, 105855. https://doi.org/10.1016/j.oraloncology.2022.105855
© 2022 The Authors. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
https://creativecommons.org/licenses/by/4.0/
https://urn.fi/URN:NBN:fi-fe2022101161583
Tiivistelmä
Abstract
Background: Free flap surgery due to the cancer of the head and neck includes high risk of postoperative complications and a five-year mortality up to 50%. We aimed to study the relation between the quality of life (QoL) reported two years after the operation and the mortality during a next three-year follow-up. We aimed to study the relation between the quality of life (QoL) reported two years after the operation and the mortality during a next three-year follow-up.
Methods: Free flap surgery due to the cancer of the head and neck includes high risk of postoperative complications and a five-year mortality up to 50%. We aimed to study the relation between the quality of life (QoL) reported two years after the operation and the mortality during a next three-year follow-up. We aimed to study the relation between the quality of life (QoL) reported two years after the operation and the mortality during a next three-year follow-up.
Results: A total of 14 (26.4%) patients died during the follow-up. The RAND-36 scores of the deceased were lower in domains “general health”, “energy”, “emotional role functioning” and “emotional well-being”. In UW-QOL tool, the domains “swallowing“ and “mood”, as well as experienced QoL were lower in the non-survivors. In EORTC QLQ assessment the non-survivors reported lower QoL in domains “global health status“, “physical functioning”, “role functioning“, “swallowing”, and “felt ill“.
Conclusions: Based on our results, poor long-term survival is related to poor QoL reported two years after surgery. The difference was found in general domains of QoL tools indicating that poor QoL is a surrogate of chronic health problems having an impact on the long-term survival.
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